TReXome DB

TReXome DB was built to identify new exon skipping targets for ASO therapy by focusing on genes with protein tandem repeat domains. It offers customizable filters (by exon frame, repeat count, exon spanning or not) and includes a curated list of disease-associated genes, and integrates a 3D model viewer of the proteins for visualization and structural context. This unique focus on repeat-rich domains may reveal therapeuti opportunities often missed by conventional approaches.

Click on any protein in the table above to explore its 3D structure with highlighted repeat domains, and to view detailed genomic information.